Poisonous Concoction Pathfinder

Last Updated: 18 May 2023

The Forbidden Sanctum 3.20

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The Poisonous Concoction Pathfinder is a Leaguestart Allrounder that kills enemies by throwing Poisonous Flasks while being able to facetank most enemies.

This build doesn't require any specific Uniques and is incredibly easy to gear. Therefore it excels for new players trying to learn and explore the game.

Gear Overview

Strengths and Weaknesses

DifficultyVery Low

Skills Breakdown

Poisonous Concoction is an unarmed skill that throws flasks at enemies, poisoning them in the process.
Whenever you attack with it, you remove 2 Life Flask Charges (if possible). Then, you deal extra damage equal to a percentage of the Life that would've been recovered if the Life Flask in question was used.
This means that crafting your Flasks is extremely worthwhile, similar to how other builds craft their weapons.

Ascendancy Breakdown


The Pathfinder enhances your Flasks and Poison Damage while giving you a much needed form of Life Recovery.

  • Nature's Reprisal increases your Damage and gives you much needed Area of Effect.
  • Master Toxicist grants us a Damage bonus and spreading Poisons whenever an enemy dies.
  • Nature's Adrenaline increases our Movement and Attack Speed, but more importantly enables us to take:
  • Master Surgeon which Recovers us 6% Life whenever we activate a Flask. This can be automated using certain combinations of mods, which are explained in detail later in the article.

For more Information on how to get your Ascendancy Points, check out our Lab Guide.

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