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Serpent Venom Druid Guide

Season 2

Last Updated:May 20, 2025|Changelog|FAQ

The Serpent Venom Druid taps into the primal power of nature, taking on the fearsome Swarmblade Form to become a venom-infused predator. This build unleashes a single, devastating Poison Damage Over Time, spreading rot and venom with every step. This is the pinnacle of Poison builds, turning the battlefield into a toxic wasteland.

This is a Melee build that spams Serpent Strike via Armblade Slash and scales Poison Damage Over Time. Its Damage primarily comes from applying as many Poison and Frostbite stacks on the target to get enormous Damage multipliers for Serpent Venom. Summon Thorn Totem and Tornado apply most of the stacks, while Summon Spriggan grants powerful defensive and offensive buffs. This build also scales in an unconventional way, gaining multipliers from Melee Critical Strike Chance and Vitality.

This setup works without any Uniques, but Weaver's Gift is essential for sustain, as it's the only source of Leech. Additionally, items like Serpent's Milk, Peak of the Mountain, and Ornate Heorot Idol with Chance on hit to summon a Thorn Totem enable the absurd damage scaling.

Overall, the Serpent Venom Druid exceeds expectations in Endgame. If you are looking for a top-tier tank with insane Poison Damage Over Time, this is the build for you!

CLICK the Planner for Gear Progression
Are you Level 70?

This build guide assumes you have a Level 70 Character.
Reach Level 70 with our Primalist Leveling Guide.
Check our Tier Lists to know how this build performs in the current patch.
If you are looking for a different playstyle, check all our Build Guides!

Pros
  • Simple Playstyle
  • Top-Tier Tankiness
  • No Snapshot Needed
  • Incredible Single Target DPS
Cons
  • Ramp Up Damage
  • No Immunity Skill
  • Average Clear Speed
  • No Long Range Traversal Skill

Skills

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Serpent Venom Druid

Swarmblade Form

This is a permanent Swarmblade Form build. This setup converts Poison chance into Frostbite chance with Frost Bites, balancing stack distribution between the two to maximize the benefits from Shattered Immunity in Serpent Strike. Armblade Slash procs Tornado, applying even more Ailment stacks, while Needle-Like Sting provides valuable base Critical Strike Chance.

Click the Nodes at the bottom to see Skill Tree Progression
!
Extra Skill Points

Skills showcase extra Skill Points in case you find +Level of Skills that may not be included in the Planners.

Passives

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Serpent Venom Druid
Click the Nodes at the bottom to see Passive Tree Progression
Passive Points

Make sure to complete the Campaign to get all your Passive Points.

Gameplay

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Serpent Venom Druid

Skill Usage/Rotation

  • Summon your Spriggan Companion.
  • Shapeshift into Swarmblade Form.
  • Attack with Armblade Slash.
  • Summon Hives as needed to spawn Locusts minions.

Bossing

  • Position your Hives strategically to keep them alive longer.
  • Use Dive or Evade to dodge telegraphed Boss attacks.

Gear, Idols & Blessings

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Serpent Venom Druid
Serpent Venom Druid
Hardcore Variant
Speedfarm
  • Get as much Crit Chance and Vitality as possible to maximize Fast Acting Toxins and Spirit Viper.
  • Idols provide a lot of power, especially Ornate Heorot Idols with Chance on hit to summon a Thorn Totem.
  • Blessings provide a lot of damage, focus them early for a big power spike.
  • Serpent's Milk also grants a huge amount of power, use it even without Legendary Potential.
  • Weaver's Gift is your only source of Leech. Use any you find, but ideally roll Melee Critical Strike Chance on it. Bleeding Heart and Rotmind can be used before you find one to get access to Leech.
  • Peak of the Mountain and Foot of the Mountain are easily obtainable from the Lightless Arbor.
  • Rule of the Simoon automatically casts Tornado, helping you hit enemies often and apply more Ailments. It's worth using even without any Legendary Potential.
CLICK the Planner for Gear Progression
  • Brewmaster's Buckle is an Armor base Belt with Endurance, excellent defensively. It also serves as a panic button, as Potions used grants you Endurance Threshold. This effect can stack. It also grants Vitality, a multiplier for Serpent Venom.
  • Mantle of the Pale Ox has amazing stats, especially with a Minion, and this build has plenty. It also provides +2 Levels to Swarmblade Form.
  • Target farm Twisted Heart of Uhkeiros from Emperor of Corpses. The Health Implicit and Strength it provides are highly valuable. Additionally, it grants +1 Level to Tornado.
  • Bastion of Honour is a great shield for Strength stacking builds. You can easily cap your Block Chance with 86 Strength. Use it even without Legendary Potential.
  • Red Rings of Atlaria are amazing since you easily reach the Attributes requirements. They help immensely with Resistances gearing and grant Damage Reduction.
  • Shattered Worlds' offensive and defensive stats makes it an amazing chase item. Good luck on Uber Aberroth!
  • For Hardcore, survivability takes priority. Health rolls are prioritized over damage in certain cases, such as on Serpent's Milk and Rule of the Simoon.
  • Seed of Ekkidrasil is great due to the build's high Rage sustain, as damage dealt to Mana before Health works with Rage. This essentially provides Damage Reduction.
  • Shattered Worlds and Advent of the Erased go hand in hand. Shattered Worlds gives permanent Haste, which enables the massive Damage Reduction from Advent of the Erased.
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  • The build has so much damage that you can swap a few Items and Passives for extra Movement Speed without sacrificing too much power or tankiness.
  • Bleeding Heart is now the main source of Leech.
  • Slam Endurance on Twisted Heart of Uhkeiros and invest into Chitinous Plating Passive to make up for losing Endurance on Boots and Belt.
  • Shard of the Shattered Lance grants Deicide on killing a Rare or Boss enemy, giving 20% more damage and 20% more Movement Speed. Yes, it's a multiplicative bonus to Movement Speed.
  • To squeeze out even more Movement Speed, Ward Trail and Razorfall are staples in speedfarm setups.
  • While more Movement Speed can be stacked with additional gear, this setup is still focused on speed and strikes a strong balance between mobility, damage, and survivability.
CLICK the Planner for Gear Progression
Crafting and Idols

Learn the basics for crafting gear with our Beginner Crafting Guide.
Make sure to complete the Campaign to get all your Idol Slots.

Build Scaling

Season 2 - Tombs of the Erased
Serpent Venom Druid

Offensive Stats

  • Vitality
  • Shared Chance to apply Poison on hit
  • Shared Chance to apply Frostbite on hit
  • Flat Melee Critical Strike Chance
  • Increased Critical Strike Chance
  • Strength
  • Dexterity
  • Increased Melee Attack Speed
  • Increased Poison Damage Over Time
  • Poison Penetration

Defensive Stats

  • Health
  • Armor
  • Endurance
  • Dodge
  • Block Chance
  • Block Effectiveness
  • Leech

Scaling Tips

Damage
Defense
  • Vitality: Spirit Viper
  • Melee Crit Chance: Fast Acting Toxins, scales past 100%.
  • Shattered Immunity: This is effectively two seperate multipliers: one from Poison stacks, and the other from Frostbite stacks. Balancing both as much as possible maximizes Damage.
  • Rule of the Simoon: Procs Tornadoes, which can trigger each other, increasing the number of Ailments applied. This synergises with Shattered Immunity.
  • Serpent's Milk: The massive chance to Poison on Minion Hit works exceptionally well with Summon Thorn Totem's explosions.
  • Impervious: Provides 20% Damage Reduction against Hits at maximum stacks.
  • Ursine Strength: Provides 16% Damage Reduction from Nearby enemies.
  • Mantle of the Pale Ox: Up to 24% of damage is redirected to your highest Health minion, and this build has plenty.
  • Seed of Ekkidrasil: Up to 28% of damage is dealt to Mana before Health. This also works with Rage.
  • Bastion of Honour: Easily cap Block Chance with Strength stacking builds.
  • Brewmaster's Buckle: Potions used grants you Endurance Threshold. This effect can stack.
  • Red Ring of Atlaria: Provides 10% Damage Reduction if you reach the Attribute requirements.
  • Shattered Worlds: Grants up to 10% Damage Reduction.
  • Summon Spriggan: Can optionally be Snapshotted for a significant amount of Dodge. Check the LEPlanner for the gear setup.
Learn More

Our Damage Explained Article covers all you need to know to scale Damage.
Learn all you need to know to scale Defense with our Defense Explained Article.

Loot Filter

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Serpent Venom Druid

Loot Filters are critical in Last Epoch. Making sure you highlight all the related valuable Item Bases, Affixes, Uniques and Idols is necessary to ensure your character's progression. Click on the Generate Loot Filter button down below then use the Paste Clipboard Contents button in-game to import it!

Here is the Endgame Loot Filter for this build:

Loot Filters Explained

Learn how to load and make Filters with our Loot Filter Guide.

FAQ & Mechanics

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Serpent Venom Druid

Once a guide is released, many players have questions on why and how we are approaching certain choices. In this section you can find the answers to the questions that have been asked the most.

Video Guide

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Serpent Venom Druid

Summary

Season 2 - Tombs of the Erased
Serpent Venom Druid

The Serpent Venom Druid is a Melee Swarmblade Form build that strikes swiftly with a single, massive, Poison Damage Over Time. This Druid excels in Endgame, offering excellent tankiness alongside top-tier damage.

  • This is a permanent Swarmblade Form build, therefore uses Rage instead of Mana.
  • Serpent Venom is the main damage source. It consists of a single stack of Poison Damage Over Time and prevents critical strikes.
  • The playstyle is straightforward: just Melee Attack.
  • It scales in unique ways: from Vitality, Melee Critical Strike Chance even beyond 100%, and Poison and Frostbite stacks on enemies.
  • Weaver's Gift is essential for sustain, as it's the only source of Leech.
  • While they are not mandatory, items such as Serpent's Milk, Peak of the Mountain, and Ornate Heorot Idol with Chance on hit to summon a Thorn Totem enable the absurd damage scaling.

Credits

Written by BinaQc.
Content Reviewed by Volca.

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